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Importantly, as the chief brain source of APOE, astrocytes, especially those expressing the APOE4 allele, promote A aggregation, tau pathologies, BBB breakdown, and cerebrovascular dysfunctions (Wang M
Psychiatry 164 , 11491159 (2007)
In this manuscript, we meticulously traced the origin of each natural product mentioned in all the original research papers and precisely provided their authoritative taxonomic and family information (Supplementary Appendix 15)
Instead, doctors usually prescribe one medication at a time and may switch treatments if needed
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